12/12/2009

Fixing Fatal Tamiflu Resistance in Pandemic H1N1. -- (Recombinomics)

 

Thus, when the H274Y in pandemic H1N1 was found in an isolate that had D225E, there was concern that the receptor binding domain could facilitate the spread of H274Y via a fit H1N1.  These concerns were increased by....

The fixing of H274Y In seasonal fu was linked to the jumping of H274Y and key polymorphisms from one genetic background to another via recombination.......

In pandemic H1N1, both H274Y and D225G have been found on multiple genetic backgrounds raising concerns that H274Y will soon be fixed in pandemic H1N1 and this fixing may be linked to receptor binding domain changes associated with severe and lethal infections........


Fixing Fatal Tamiflu Resistance in Pandemic H1N1

10:44 Écrit par Dr MSFV | Lien permanent | Commentaires (0) |  Facebook |

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