E627K Circulation in Pandemic H1N1 Patients in the Netherlands. -- (Recombinomics)
......The levels of H1N1 have increased dramatically in the northern hemisphere and the rise is associated with the start of a new school year. In many areas, cases are reported to be more severe leading to deaths among previously healthy pediatric cases in middle schools and high schools. The targeting of students and the increase in fatal cases may be linked to viral load, which cold increase dramatically in viruses with E627K when the temperature drops...........mixtures of virus could lead to higher levels in the upper respiratory tract initially, which could lead to higher levels of E627 in the lower respiratory tract due to initial copying by E627K. Thus, a mixed infection could produce high levels of two different viruses in the upper and lower respiratory tract.