23/09/2009

Efficient Transmission of Tamiflu Resistant Pandemic H1N1. -- (Recombinomics)

 

.....The fixing of H274Y in seasonal flu raised concerns that a similar scenario would develop in pandemic H1N1 since Tamiflu was widely used, and the H274Y in seasonal H1N1 provided a large reservoir of donor sequences fro a jump to pandemic H1N1.  Initial concerns suggested two different mechanisms for the jump, involving the exchange of genetic information via reassortment or recombination.  Both mechanisms required a dual infection, but the reassortment would replace the swine N1 with human N1....

Efficient Transmission of Tamiflu Resistant Pandemic H1N1

15:51 Écrit par Dr MSFV | Lien permanent | Commentaires (0) |  Facebook |

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